Tetanus Antibodies
|
Assay |
Tetanus antibodies |
|
Key Words |
Tetanus antibodies, TETA |
|
Specimen Collection |
Serum (brown) |
|
Turnaround time |
21 days This test is referred to another centre: Department of Clinical Chemistry and Immunology Level 4 Addenbrookes Hospital NHS Trust |
|
Test indications |
This trest is used to assess the T cell dependent antibody pathway. Patients should have this test done in the following clinical circumstances: a) Patients, especially children, with recurrent bacterial sepsis; particularly of the upper and lower respiratory tract. b) Patients with invasive disease caused by encapsulated organisms. c) Patients with selective antibody deficiency states and in monitoring immunoglobulin replacement therapy in such patients. d) Immunological reconstitution following Bone Marrow Transplant. e) Patients having haemoglobinopathies or who are due to undergo or who have had a splenectomy should have their levels of antibodies to encapsulated bacteria (i.e. pneumoccocal & Hib) monitored. f) patients with radiographical evidence of bronchiectasis.
Knowledge of vaccine history is imperative for correct interpretation. Specific clinical symptoms are also advantageous. If a poor response if found, patients will be required to be vaccinated and retested 4 week post. Specific interpretation is given for each patient result |
|
Methodology |
Enzyme immunoassay |
|
Interferences |
Contact referral centre |
|
Reference Range |
Minimum protective level 0.1 IU/mL Optimum protective level >1.0 IU/mL |
|
Analytical error |
Contact referral centre |
|
Reference change value |
N/A |
