Assay

Skin antibodies

Key Words

Skin antibodies, SKIN

Specimen Collection

Serum (brown)

Turnaround time

21 days

Test indications

Antibodies to various components of skin are associated with autoimmune blistering disorders. Antibodies to basement membrane zone antigens are associated with bullous pemphigoid, herpes gestationis and epidermolysis bullosa acquisita. Antibodies to the intercellular substance of the epidermis are associated with pemphigus vulgaris and pemphigus foliaceus. These tests are complementary to direct immunofluorescence examination of skin biopsies in these conditions.

Methodology

Indirect immunofluorescence

Interferences

No known methodological interferences

Reference Range

N/A

Analytical error

N/A

Reference change value

N/A