Alkaline Phosphatase
|
Assay |
Alkaline Phosphatase |
|
Key Words |
ALP, ALKP |
|
Specimen Collection |
Serum (brown), Plasma (orange) |
|
Turnaround time |
8hrs |
|
Test indications |
A rise in the alkaline phosphatase occurs with all forms of cholestasis, particularly with obstructive jaundice. It is also elevated in diseases of the skeletal system, such as Pagets disease, hyperparathyroidism, rickets and osteomalaecia, as well as with fractures and malignant tumours. A considerable rise in the alkaline phosphatase activity is sometimes seen in children and juveniles. It is caused by increased osteoblast activity following accelerated bone growth. |
|
Interferences |
EDTA (from FBC bottles) can cause falsely low results, please ensure the correct draw order is adhered to |
|
Reference Range |
Neonate: 70-380 U/L Infant to 16 yrs: 60-425 U/L Adult: 30-130 U/L |
|
Analytical error [1] |
2.6% |
|
16.3% |
|
|
Minimum retesting interval |
Liver function test requests made within 2 days of a previous request on a patient are intervened |
