Macroprolactin

Printer-friendly versionPrinter-friendly version

 

Macroprolactin
MPROL
Serum (brown), Plasma (orange)
24hrs
Macroprolactin is an immunoglobulin-bound form of circulating prolactin which can cause falsely elevated serum prolactin concentrations. It is tested by measuring prolactin recovery on polyethylene glycol treated samples

Recovery >60%: Sample contains mostly monomeric prolactin. Recovery between 40 and 60% - gray zone: In addition to monomeric prolactin, sample also contains macroprolactin and/or oligomeric prolactin. Results need to be reported as such. Further assessment is necessary (e.g. gel filtration chromatography) Recovery <40%: Sample contains mostly macroprolactin and/or oligomeric prolactin. Results need to be correlated to clinical findings.

No known common methodological interferences.

N/A
4.6%
N/A