Assay

Serum Free light chains

Key Words

Serum free light chains ( SFLC), Kappa, Lambda

Specimen Collection

Serum (Brown). Upon receipt the sample is centrifuged and stored refrigerated

Turnaround time

1 week

Test indications

Used in the diagnosis and monitoring of monoclonal gammopathies, including MGUS and Myeloma.

Methodology

Turbidimetry

Interferences

The methodology used is known to be subject to ‘antigen excess’ which can cause false results (low or high). Checks are in place within the laboratory for antigen excess, but please feel free to contact us if you have any queries regarding a result.

Reference Range

Normal adult serum range (95th percentile)

Kappa 3.3-19.4mg/L

Lambda 5.71-26.3 mg/L

Kappa/Lambda ratio 0.26-1.65

Analytical error

N/A

Reference change value

N/A