Pyruvate Dehydrogenase Antibodies
Assay |
Pyruvate dehydrogenase antibodies |
Key Words |
Pyruvate dehydrogenase antibodies, PYDH, M2, LAB |
Specimen Collection |
Serum (brown) |
Turnaround time |
14 days |
Test indications |
The subtypes of antimitochondrial antibodies (see above in liver auto-antibodies) associated with primary biliary cirrhosis are M2, M4, M8 and in early disease M9. Antibodies to pyruvate dehydrogenase subunits are M2 antibodies and are present in most patients with PBC. Testing for pyruvate dehydrogenase antibodies is requested by the lab when anti-mitochondrial antibodies are detected by the liver antibody screen. |
Methodology |
Euroline Immunoblot |
Interferences |
None |
Reference Range |
Negative |
Analytical error |
N/A |
Reference change value |
N/A |
Minimum retesting interval |
Repeat testing of pyruvate dehydrogenase antibodies is not usually indicated. Please contact the Immunology laboratory if a repeat is required. |