Voltage Gated Potassium Channel Antibodies
Assay |
Voltage gated potassium channel (VGKC) antibodies |
Key Words |
Voltage gated potassium channel antibodies, VGKC |
Specimen Collection |
Serum (Brown) and or CSF |
Turnaround time |
14 days
This test is referred to another centre: Churchill Hospital Old Road Headington Oxford OX3 7LE 0300 304 7777
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Test indications |
Potassium channel antibodies are found in patients with acquired neuromyotonia (40-50%), Morvan’s syndrome, limbic encephalitis (Paraneoplastic and idiopathic) as well as patients with facio-branchial dystonic seizures (FBDS). Both Morvan’s and Limbic encephalitis can be associated with thymoma or small cell lung carcinoma (SCLC).
VGKC antibodies have recently been renamed VGKC-complex antibodies, as it is now recognised that the VGKCs are tightly complexed with other proteins. The most common complex proteins discovered are LGI1 and CASPR2. These proteins will be tested automatically if VGKC result is positive.
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Methodology |
Contact referral laboratory |
Interferences |
Contact referral laboratory |
Reference Range |
Contact referral laboratory |
Analytical error |
Contact referral laboratory |
Reference change value |
N/A |