Assay

Muscle specific kinase (MuSK) antibodies

Key Words

Muscle specific kinase antibodies, MusK

 Specimen Collection

Serum (brown)

Turnaround time

14 days   

This test is referred to another centre:

Department of Immunology

The Churchill Hospital

Oxford

OX3 7LJ

Tel: 01865 225995                                                                                                                                                                  

Test indications

The classical autoantibody in myasthenia gravis (MG) is the anti-acetylcholine receptor antibody. In around 20% of cases of myasthenia gravis the AChR Ab is negative, and some of the remainder have an alternative autoantibody against muscle-specific kinase (MuSK). MuSK antibodies are involved in the pathogenesis of MG more commonly in adults than children.We do not automatically request MuSK antibodies, but if you strongly suspect myasthenia gravis and the AChR antibody is negative, please tell the laboratory and we will request this test from a reference laboratory.

Methodology

Contact referral centre

Interferences

Contact referral centre

Reference Range

N/A

Analytical error

Contact referral centre

Reference change value

N/A