HMGCoA reductase antibodies
Assay |
3-hydroxy-3-methylglutaryl-CoA reductase autoantibodies |
Key Words |
HMGCoA reductase antibodies; HMG; Statin associated myopathy; necrotising myopathy |
Specimen Collection |
Serum (Brown) |
Turnaround time |
14 working days
This test is referred to another centre: Churchill Hospital Old Road Headington Oxford OX3 7LE 0300 304 7777
|
Test indications |
HMGCR autoantibodies have been shown to be a myositis specific autoantibodies that are strongly associated with immune mediated necrotising myopathy. HMGCR autoantibodies positive patients present with progressive, irritable myopathy of the proximal muscles, with oedema on MRI and a creatinine kinase typically 10x the upper limit of normal.
|
Methodology |
Chemilluminescence |
Interferences |
Contact referral lab |
Reference Range |
Negative = <14.9 CU/ml Equivocal = 15-24.9 CU/ml Positive = >25 CU/ml |
Analytical error |
Contact referral lab |
Reference change value |
Contact referral lab |