Assay

Beta-2-glycoprotein-1 (IgG)

Key Words

Beta-2 glycoprotein 1 abs (B2IG)

Specimen Collection

Serum (Brown)

Turnaround time

7 Days

Test indications

Beta-2-GP-1 is a phospholipid binding protein and antibodies directed against this antigen are seen in patients suffering from the Anti-Phospholipid Syndrome (APS). This test is recommended in patients suspected of having APS in whom the lupus anticoagulant and anti-cardiolipin assays are negative, and can be helpful in other situations described in the 2012 BCSH guidelines (available from:

British Journal of Haematology | Wiley Online Library

Methodology

Enzyme immunoassay

Interferences

No known methodological interferences

Reference Range

Negative <7 U/mL

Equivocal 7-10 U/mL

Positive >10 U/mL

Analytical error

Contact laboratory x8454

Reference change value

N/A