Assay

Interferon Beta Binding antibodies

Key Words

Interferon Beta Binding abs , INBA

Specimen Collection

Serum (Brown)

Turnaround time

32 days

This test is referred to another centre:

Department of Clinical Chemistry and Immunology

Level 4

Addenbrooke’s Hospital NHS Trust

Hills Road

Cambridge

CB2 2QQ

01223 217215

Test indications

Multiple sclerosis patients receiving treatment with recombinant interferon-beta (IFN-β) products often develop IFN-β binding antibodies and neutralising antibodies. Development of these antibodies may reduce the clinical efficacy of the treatment.

Methodology

Multiplex assay

Interferences

Presence of therapeutic IFN- β can give a false negative result

Reference Range

NA

Analytical error

Contact referral lab

Reference change value

Contact referral lab