Assay

Glycine Receptor antibodies

Key Words

Glycine receptor abs, GLYA

Specimen Collection

Serum (Brown) (CSF is not required but can be analysed if required)

Turnaround time

14 days

This test is referred to another centre:

Churchill Hospital

Old Road

Headington

Oxford

OX3 7LE

0300 304 7777

Test indications

These antibodies are particularly associated with PERM (Progressive encephalomyelitis with rigidity and myoclonus) and stiff person syndrome. Glycine receptor antibodies were associated with neoplasms in about 10% of a series of 52 patients (mainly thymoma and lymphoma).

Carvajal-Gonzalez et al. Brain, Volume 137, Issue 8, August 2014, Pages 2178–2192, https://doi.org/10.1093/brain/awu142

Methodology

Cell based assay

Interferences

Contact referral laboratory

Reference Range

Contact referral laboratory

Analytical error

Contact referral laboratory

Reference change value

 N/A